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Cala Trio medical device shown at angle

Cala TrioTM

is proud to help veterans with essential tremor.

Meet Cala Trio

The first wearable device designed from the ground up treat essential tremor (ET). The therapy delivers meaningful results for the majority of patients after just a single session.

Cala Trio maybe available for eligible veterans with essential tremor, and requires a prescription from your VA health provider.

How it works

Surface stimulation delivered at your wrist is thought to disrupt the central tremor network in your brain that causes the hand tremor.

  • Developed through Clinical Studies
  • 64% of patients reported having persistent relief for an average of 94 minutes1
  • 54% of patients' tremor power improved by at least 50%1
  1. The stimulation interrupts the tremor in the ventral intermediate nucleus of the thalamus part of the brain
  2. Gentle stimulation is sent to the median and radial nerves, traveling to the brain
  3. Cala Trio measures your specific tremor

A new approach to managing essential tremor


Cala Trio is a wrist worn wearable therapy. No surgery or invasive procedures needed.

Drug Free

Unlike pharmaceutical treatments for essential tremor, Cala Trio does not have any permanent or systemic side effects.

Easy to Try

There is no perfect treatment for everyone. If Cala Trio is not right for you, simply return within 90 days to your VA Prosthetics Department.


The image below is an actual patient test (Archimedes Spiral Task) before and after a 40-minute stimulation therapy with Cala Trio.

2 Lin PT, Ross EK, Chidester P, et al. Noninvasive neuromodulation in essential tremor demonstrates relief in a sham-controlled pilot trial. Mov Disord. 2018;33(7):1182-1183. doi: 10.1002/mds.27350.

Patient stories


“Using the Cala Trio changed my personality and my life. It made me more confident. It allows me to be free and I’m not feeling like people are looking at me.”



“I noticed how easy it was to eat I texted my wife to tell her what my experience was. When I was texting I thought how easy it is to text ... After I texted her that, I still remember, I held up my hand, I thought so this is what it feels like to feel normal.”



“I would always start my therapy with the Cala Trio in the morning when I first woke up. I would get my kids off to school so I prepare lunches and everything while using it ... all those day-to-day tasks that I struggled with I was able to complete thanks to the Cala Trio.”


Find out if Cala Trio is right for you

Take a brief quiz to see Cala Trio is right for you and receive a free doctor discussion guide.

Indication for Use

Cala Trio is indicated to aid in the transient relief of hand tremors in the treated hand following stimulation in adults with essential tremor. Please refer to the Safety Information for a complete listing of warnings and cautions.

Caution: Federal law restricts this device to sale by or on the order of a physician.

Safety Information

This section lists general Warnings and Cautions related to using Cala Trio.


  • To avoid the risk of electric shock, burns, electrical interference, or death, do not use Cala Trio if you have:
    • A pacemaker
    • An implanted defibrillator
    • Other implanted electronic devices, or implanted metal in the wrist
  • Do not use Cala Trio while:
    • Sleeping
    • Driving
    • Bathing
    • Operating machinery
    • Doing any activity in which possible involuntary muscle contractions due to therapy may cause undue risk of injury.
  • Do not use Cala Trio:
    • Near the head
    • Directly on the eyes
    • Covering the mouth
    • On your upper back
    • Over the heart area
    • On diseased skin
  • Do not use Cala Trio on the neck.
    • Doing so can cause severe muscle spasm, resulting in closure of the airway, difficulty with breathing, or adverse effects on heart rhythm.
  • Do not use Cala Trio on the chest.
    • Introduction of electric current into the chest may cause rhythm disturbances to the heart, which could cause death.
  • Do not apply Cala Trio near the chest.
    • This may increase the risk of abnormal heart rhythm (arrhythmia).
  • Do not apply Cala Trio over open wounds or rashes, or over swollen, red, infected, or inflamed areas or skin eruptions (e.g., phlebitis, thrombophlebitis, varicose veins, etc.).
  • Do not apply Cala Trio over—or in proximity to—cancerous lesions.
  • To prevent electrical shock, do not immerse Cala Trio in water.
  • Do not wear Cala Trio while performing activities where Cala Trio is under water (e.g., swimming or bathing).
  • Do not use Cala Trio simultaneously with:
    • High-frequency surgical equipment, as this may result in electrical burns and/or possible damage to Cala Trio
    • Electronic- monitoring equipment (e.g., cardiac monitors, ECG alarms), which may not operate properly when Cala Trio is in use
  • To prevent an explosion hazard and possible injury, stop Cala Trio therapy when at a refueling place (e.g., gas station).
  • Do not use Cala Trio near flammable fuel, fumes, or chemicals.
  • Physician approval should be obtained by your prescribing physician before using Cala Trio if you have any implanted devices at the site of stimulation.
  • Cala Trio provides chronic electrical stimulation, the long-term effects of which are unknown.
  • To prevent uncomfortable therapy, skin irritation and/or shock, the user should wet their wrist before donning Cala Trio.
  • Therapy at an intensity that is too high can cause discomfort in your wrist and/or hand, muscle contraction, or skin irritation.
  • Some may experience skin irritation, an allergic reaction, or hypersensitivity to the therapy or the band.
  • Avoid removing Cala Trio from your wrist during therapy.
  • To charge Cala Trio, use only the Cala Trio Base Station.
  • The cord on the charger may present a choking hazard. Keep away from children.


  • Use Cala Trio only as directed by this Patient Guide or your physician.
  • Do not use Cala Trio if you have suspected or diagnosed epilepsy or other seizure disorder.
  • Do not use Cala Trio if you are pregnant.
  • Higher stimulation levels may be associated with potential for increase in skin irritation, including electrical stimulation burns of the skin, which may cause focal pinpoint edema, erosion and crusting.
  • Store Cala Trio in the included microfiber bag to prevent exposure to dust and pests.
  • To prevent damage and/or performance issues to Cala Trio:
    • Keep Cala Trio dry. Cala Trio can withstand some splashing.
    • Do not use in places with high humidity (e.g., the bathroom).
    • Do not store or transport Cala Trio or its accessories in temperatures that exceed the recommended storage temperature range: -20°C to 45°C (-4°F to 113°F).
    • Do not operate in temperatures that exceed the recommended operation temperature range of 5°C to 40°C (41°F to 104°F). Temperature extremes can damage the device and accessories.
    • Do not tamper with, modify, or attempt to perform maintenance or servicing on Cala Trio.
    • Do not use Cala Trio within 3 ½ feet of shortwave or microwave equipment.
  • To prevent damage, performance issues, increased emissions, or decreased immunity of Cala Trio, only use the accessories recommended by Cala Health with the device.
  • Use Cala Trio with caution:
    • If you tend to bleed following an injury.
    • Over areas of the skin that lack normal sensation.
  • Keep out of the reach of children and pets.
  • Cala Trio is single-patient use by the individual for whom it has been prescribed.
    • It should not be worn by anyone else, or on any other part of your body.
  • To avoid interfering with diagnostic assessments, do not wear Cala Trio during x-ray examinations.
  • To prevent Cala Trio band damage, do not pinch, pull, or twist the Band with too much force.
  • Should any technical problem occur that is not covered in the Patient Guide, please contact Cala Health at 888-699-1009 or

Adverse Reactions

The following are possible minor risks or adverse reactions that you may experience with the use of Cala Trio:

  • Discomfort with stimulation (e.g. stinging, sensation of weakness, etc.)
  • Allergic reaction to electrodes or other materials
  • Skin irritation, including electrical stimulation burns, redness and/or itching

In the unlikely event that any of the following more significant issues happen, immediately stop using Cala Trio and contact your physician.

  • Signs of significant persistent skin irritation, sores, electrical stimulation burns, or lesions at the site of the stimulation
  • Significant and persistent increase in muscle tightness or stiffness
  • A feeling of chest pressure during stimulation
  • Swelling of your arm, wrist, or hand

Skin Care Guidelines

The device works by electrically stimulating nerves through the skin. It is important to inspect your skin where it contacts the electrodes to minimize risk of irritation. To promote good electrode connection and healthy skin, try some of these skin care guidelines:

  • Wet your wrist before donning Cala Trio
  • If there is any excess oil or lotion on your wrist, wash with soap and water and rinse well before wearing Cala Trio
  • Always check your skin for irritation, redness, or rash when putting on and taking off Cala Trio

1 Isaacson SH, et al. Tremor and Other Hyperkinetic Movements. 2020;10:29. DOI: