Cala Trio™
therapy meets
you where you
are, when
you need it.
Cala Trio therapy is a groundbreaking treatment designed to temporarily and effectively reduce your hand tremor. It is the first and only non-invasive therapy that directly targets the source of the tremor by gently stimulating the wrist nerves with electricity (neuromodulation) and targeting the root cause of essential tremor.1
The Cala Trio device is FDA-cleared, safe, effective, and individually calibrated to each patient's unique brain signal pattern.1–3Base Station
Charging base station with a magnetic charger.
Stimulator
Stimulator that personalizes your Cala Trio therapy for your unique tremor pattern.
Band
Replaceable 3-month band visibly labeled with size and hand which includes our proprietary surface electrodes.
How it works
1Cala Trio therapy measures your specific tremor.
2Gentle stimulation is sent to the median and radial nerves, traveling to the brain.
3The stimulation interrupts the tremor in the brain's ventral intermediate nucleus of the thalamus.
Results illustrating before and after Cala Trio therapy session.4
This image is an actual patient test (Archimedes Spiral Task) before and after a 40-minute treatment with the Cala Trio therapy.
During in-clinical evaluation after twice daily at-home use:1
71% of patients reported improvement in holding a cup of tea in Activities of Daily Living.1
68% of patients who self-rated as having “Severe or Moderate” difficulty in their activities of daily living self-rated as “Mild” or better at the end of the study. Patients reported using Bain-Finley Activities of Daily Living (BF-ADL).1
64% of patients reported persistent relief for an average of 94 minutes (standard deviation = 138; median = 60).1
Real World Evidence
Data analyzed from 22 months of real world use confirms prior clinical studies showing Cala Trio therapy effectively reduces tremor with no loss of effect over time and improves patient quality of life for those living with essential tremor (ET).5Contraindications: Cala Trio therapy should NOT be used by patients with an implanted electrical medical device, those with suspected or diagnosed epilepsy or other seizure disorders, or used on the treated wrist with diseased skin (e.g., swollen, infected, inflamed areas, or open wounds), or by patients who are or may be pregnant.
Review all safety information before using the Cala Trio therapy, CalaTrio.com/Safety.3
Clinical ResearchSummary
Patient Access
Cala is committed to ensuring all patients can access Cala Trio therapy. Our Cala Customer Care specialists assist in facilitating patient access to therapy:
- Benefit verification and prior authorization processing.
- Collection of medical necessity documentation working directly with the prescribing healthcare provider.
- Appealing coverage denials at no cost to the patient.
Cala is committed to ensuring all patients have access to Cala Trio therapy. If you and your prescriber decide that Cala Trio therapy is not right for you, simply return the device before the end of the 60-day return period, and you will not be held responsible for any costs.*
*Patient agreement is required; patients using Medicare benefits are not eligible. Visit our Medicare page for details.
Cala Trio Therapy Eligibility Survey
Patient Access
Cala is committed to ensuring all patients can access Cala Trio therapy. Our Cala Customer Care specialists assist in facilitating patient access to therapy:
- Benefit verification and prior authorization processing.
- Collection of medical necessity documentation working directly with the prescribing healthcare provider.
- Appealing coverage denials at no cost to the patient.
Cala is committed to ensuring all patients have access to Cala Trio therapy. If you and your prescriber decide that Cala Trio therapy is not right for you, simply return the device before the end of the 60-day return period, and you will not be held responsible for any costs.*
*Patient agreement is required; patients using Medicare benefits are not eligible. Visit our Medicare page for details.
Cala Trio Therapy Eligibility Survey
Freedom to be™
Testimonials
For the visually impaired, a full text alternative of this video is available here
| Time Frame | Visuals | Voice Over |
|---|---|---|
0:00 | Background: Image carousal with Cala Trio freedom to be logo | Background music |
0:07 | Background: Video clips of Sylvia struggling to Sylvia getting interviewed with | It’s embarrassing. It’s totally embarrassing. You’re shaking. You can’t do anything. My name is Sylvia and I’m 73 years old and I’ve had essential tremors for over 30 I was born and raised in Detroit, Michigan. I played on the Virginia Slims |
0:47 | Question screen Text: When did you first notice the Background: Sylvia getting interviewed Clips of video doing everyday | I really noticed it about five years ago. A safe deposit box, you know how you go in It’s annoying! It’s so annoying and someday in the beginning there were even tears. I told everybody I was going to quit playing because I couldn’t putt. You can’t do |
1:22 | Question screen Text: Have you tried other treatment Background: Sylvia getting interviewed Clips of video doing everyday | I went to a doctor and they put me on this medication. Then they said, well, take Those tremors will bring you down. They’ll bring you down. In my desperation I I just can’t do it. I’m scared to death. The people working with Cala Trio have done quite a service for those of us who are Cala Trio came along and I’m loving it. I can stimulate for 40 minutes. It allows me to Cala Trio, as I’ve said, it’s not going to stop the tremors but it makes you do things Go tell your doctor about it. And tell him or her you would like to try it. Tell the Now I don’t quit. It’s like you want to play let’s play. We got this. |
3:15 | Background: Cala trio on docking station with Screen Text: calatrio.com Federal law restricts this device to | Background music |
Cala Trio came along and I’m loving it.
For the visually impaired, a full text alternative of this video is available here
| Time Frame | Visuals |
|---|---|
| 00:00:03 | I’m Holly. And I would say that the difference with a Cala treatment is indeed the difference between night and day. It’s the difference between feeling very apprehensive and feeling more confident. I think the first time that I reallynotice hand tremor was about my late 40s. |
| 00:00:30 | But it was when I was in my mid-50s that I decided that it was probably a good time to see a neurologist and figure out if I did indeed have Parkinson’s. |
| [MUSIC] | |
| 00:00:49 | Essential tremor has affectedmy life particularly in a dining situation. And it would be difficult for me to drink without spilling. It was difficult keep food on my fork. It’s difficult to read, holding a book or a magazine, newspaper. In the cooking field I have trouble keeping a knife steady when the tremor is really bad. |
| [MUSIC] | |
| 00:01:27 | I have so many reactions to medication that I decided I didn’t even want to pursue medication. And I knew that I did not want to pursue brain stimulation or focused ultrasound. And then two people from Cala came to interview people that might be interested in being in one of the testing programs. And I think I was the first person that shot up my hand. |
| 00:01:58 | I was so excited about it because I just knew that it was going to be something very special. When I took the prescription into my physician he had absolutely no clue what Cala Trio was. And I took the packet of information I took into him and was going to go on the website and read all about it. |
| 00:02:26 | And he was pleasedto be able to give me the prescription, so that I could get my own. |
| 00:02:36 | Cala Trio has changed my life. And it even bringstears to my eyes. It has made such a difference in my life. Being able to read without the book shaking all over the place, feeling more secure cooking, using a knife. One of the best parts is being able to eat and drink without having a tsunami in my cup and not having food fall off my fork. |
| 00:03:12 | It’s just so nice to be able to go about my normal business,knowing that I’m not going to be trembling the way that I had prior. It’s an amazing, amazing medical device. I want to spread the word because it is so effective. My prayer is that many people will come to know about Cala and Cala Trio. |
| [MUSIC] | |
| 00:03:45 | [END OF TRANSCRIPT] |
Cala Trio has changed my life. And it even brings tears to my eyes. It has made such a difference in my life.
For the visually impaired, a full text alternative of this video is available here
| Time Frame | Visuals |
|---|---|
| 00:00:00 | I’m Beverly. I have an essential tremor. And I’m dealing with it better thanks to my little miracle-my Cala Trio. I was not formally diagnosed with essential tremor until about maybe 15 years ago. I had complete work up by my neurologist. |
| 00:00:30 | He ruled out any other causeof my movement disorder and diagnosed essential tremor. I’m one of four children. And of the four of us three have essential tremor. My ET has progressed farther than my sister and my brother’s have progressed. |
| [MUSIC] | |
| 00:01:07 | The hardest things for me are things like writing, feeding myself, eating and using my hands for little things–things like grooming, trimming my fingernailsand putting in earrings. These earrings were hard to get in becauseof my tremor |
| 00:01:35 | I tried every medication imaginable to treat my tremor. If it had any potential ability to reduce tremor I tried it. And there have been some real problems with that. I’ve had major falls. And it has impaired my balance to the point that I now use a walking stick, so I don’t fall. |
| 00:02:12 | I love a cup of coffee in the morning and to do the Sudoku. And now whenever I drink my coffee and the Sudoku I put on the Cala Trio. And I go to political meetings. And I had lost the abilityto take notes in meetings. |
| 00:02:37 | I can wear my Cala Trio and now I can take notes again. It doesn’t fix my tremor. It doesn’t cure my tremor. It doesn’t completely eliminate my tremor. But it reduces the intensity. Cala Trio has given me the ability to go back out into the world. |
| [MUSIC] | |
| 00:03:13 | [END OF TRANSCRIPT] |
I love a cup of coffee in the morning and to do the Sudoku.
For the visually impaired, a full text alternative of this video is available here
| Time Frame | Visuals |
|---|---|
00:00:02 | My name is Greg. I have essential tremor. Recently I went to the doctor because I had cataract surgery. And it’s really a problem for me because I know one of the first things they’re going to ask me to do is fill out a form. And my hands shake so bad and you got to write small. I just – it takes me forever. |
00:00:32 | You know, sometimes you go out to eat and I have to use a spoon in some cases because I can’t keep scrambled eggs on my fork. I have to eat scrambled eggs with a spoon. And it’s embarrassing. Water color painting is of paramount importance to me. It would be impossible for me to paint if I didn’t use the Cala Trio. I have to hold one had with the other just to sketch something. |
00:01:05 | And then when I want to paint what it is I sketch it’s a two hand operation. |
| [MUSIC] | |
00:01:14 | My doctor started me on a medication. And over the years he kept changing the medication and giving me stronger dosage. That went on for quite some time. And then over the years we ran out of the different available medication. He said that I should go and see what else is available. And that’s when Cala Health came in and talked about this device that they had that was called the Cala Trio. |
00:01:45 | It was the size of a – basically a wristwatch. It was comfortable to wear. And I was right away interested in wearing the device to see how it might help me. |
| [MUSIC] | |
00:02:04 | I had great results right from the very first time. Uh, I just continued to get great results. Different people have different results. The benefits last me about maybe two hours. I can paint. |
00:02:39 | But today they don’t they don’t do that. They appreciate the fact that when I’m wearing the Cala Trio my hands don’t shake. So it’s clear to everybody that Cala Trio works. Even my grandkids know it. |
| [MUSIC] | |
00:03:11 | [END OF TRANSCRIPT] |
I had great results right from the very first time. I can take my grandkids out for breakfast.
- Isaacson SH, et al. Tremor and Other Hyperkinetic Movements. 2020;10:29. doi:10.5334/tohm.59. As measured by Cala device following three months of repeated home use in 205 patients with essential tremor who completed the study. Many participants were also taking medication for their tremor and it was difficult to assess the effect of the device compared to medication.
- Food and Drug Administration (FDA) has cleared the Cala Trio K203288.
- Safety information. The most common reported side effects include mild to moderate skin irritation, including electrical stimulation burns, redness, and/or itching where the device touched the skin. For comprehensive safety information, visit CalaTrio.com/Safety.
- Lin PT, Ross EK, Chidester P, et al. (2018). Noninvasive neuromodulation in essential tremor demonstrates relief in a sham-controlled pilot trial. Mov Disorder, John Wiley and Sons Inc.; p. 1182–1183. Mov Disord. 2018 Jul; 33(7): 1182–1183.
- Brillman S, Colletta K, Borucki S, Lin PT, Waln O, Petrossian M, et al.. Real-World Evidence of Transcutaneous Afferent Patterned Stimulation for Essential Tremor. Tremor and Other Hyperkinetic Movements. 2022;12(1):27.
- Patient experiences are summarized from interviews featured on the Cala Health YouTube Channel. Individual results may vary; patients were not compensated for their stories.
