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Individualized therapy for essential tremor that fits with the flow of your life.
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Get StartedIndividualized therapy for essential tremor that fits with the flow of your life.




Welcome to
Cala Trio therapy
With the Cala Trio therapy, patients experience meaningful temporary tremor relief after a 40-minute wrist-worn treatment enabling them to regain their daily activities independently and confidently.1
Available by prescription only
Cala Trio therapy is the world’s only non-invasive, drug-free, wrist-worn treatment that addresses the root cause of essential tremor with electrical stimulation known as neuromodulation.
The Cala Trio device is FDA-cleared, safe, effective, and individually calibrated to each patient's unique brain signal pattern.1–3
The Cala Trio device is indicated to aid in the temporary relief of hand tremors in the treated hand following stimulation in adults with essential tremor.
Cala is committed to ensuring all patients have access to Cala Trio therapy. If you and your prescriber decide that Cala Trio therapy is not right for you, simply return the device before the end of the 60-day return period, and you will not be held responsible for any costs.*
*Patient agreement is required; Medicare patients are not eligible to participate
How it works
For the visually impaired, a full text alternative of this video is available here
Time Frame | Visuals | Voice Over |
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0:00 |
Screen Text: Talk to your doctor about Cala Trio |
Background music |
0:06 |
Video clips of patient struggling to do everyday tasks. |
Essential tremor is a benign yet life-altering condition that impairs performing day-to-day activities. Although onset typically occurs in adults fifty and older, symptoms may appear much earlier in life. |
0:20 |
Background: Patient reading a book then looking at a computer screen Screen Text: Non-invasive treatment for essential tremor |
Cala Trio, is a wrist-worn, non-invasive treatment for essential tremor. It targets the tremor network with peripheral nerve stimulation through the wrist. |
0:30 |
Background: Patient looking at a computer screen then visiting her doctor Screen Text: Requires Prescription Background: Screen of a search engine typing in URL |
Cala Trio therapy is a prescription device. Your physician may not know about Cala Trio therapy, its clinical results, or that it is now available! Forward the link calatrio.com/healthcare-professionals to your doctor so he/she can learn more prior to your appointment. |
0:50 |
Background: Patient looking at a computer visiting calatrio.com to download a Doctor Discussion Guide Screen Text: Requires Prescription Background: Screen of a search engine typing in URL |
The website has a lot of information about essential tremor and Cala Trio. If you think Cala Trio might work for you, simply download and print the Doctor Discussion Guide which includes a prescription form for your doctor. Complete the guide to give your doctor basic background information about your experiences with tremor. |
1:09 |
Background: Patient visiting her doctor with Doctor Discussion Guide Screen Text: How long have you had hand tremors? Has medication worked? Do you have the relief you want? |
Remind your doctor about your experiences with therapies. How long have you had hand tremors? How has medication worked? Do you have the relief you want? |
1:19 |
Background: Patient visiting her doctor with Doctor Discussion Guide with her hand shaking Screen Text: “I found a new therapy for my essential tremor and want to see if you will write a prescription for it so I can Try it.” |
Tell your doctor, “I found a new therapy for my essential tremor and want to see if you will write a prescription for it so I can try it. Here is some information about Cala Trio therapy.” It is easy for your doctor to prescribe Cala Trio. |
1:33 |
Background: Patient showing her tremors to doctor Images: Two hand Icon Screen Text: Select right or left hand |
There are 3 simple parts of the prescription to discuss with your doctor Select the hand you want to treat that will provide the most relief for your lifestyle. |
1:42 |
Background: Patient getting her wrist measured Images: Measuring tape icon Screen Text: Determine wrist size |
Measure your wrist to determine band size. |
1:45 |
Background: Patient doing tremor task positions Images: Icons for the two tremor positions Screen Text: Outstretched Wing beating |
Choose the tremor task that elicits the more significant hand tremor. Hold your hands stretched straight in front of you. Bend your arms to the side in the ‘wing-beating’ pose. Determine which of these postures gives you a more significant tremor. Your doctor will fax the prescription to Cala Health. |
2:02 |
Background: Patient opening a Cala Trio box Screen Text: Your Cala Trio will arrive in a few days |
Once ordered, your Cala Trio will arrive in a few days |
2:07 |
Background: Patient on the phone holding Cala Trio Screen Text: CustomerSuccess@CalaTrio.com |
Meet with our customer success team via phone or video to set-up your Cala Trio. |
2:13 |
Background: Patient showing tremor reduction enjoying activities of daily living |
Enjoy a reduction in your hand tremor. Talk to your doctor about incorporating Cala Trio therapy into your treatment for essential tremor. |
2:23 |
Background: Cala trio on docking station with logo Screen Text: calatrio.com Federal law restricts this device to sale by or on the order of a physician. Please refer to the labeling for a complete list of warning, precautions and contraindications. |
Background music |


The Cala Trio device is cleared by the FDA as an external upper limb tremor stimulator, Class II (initially under de novo DEN170028 with subsequent 510(k) clearances K182706 and K203288).
Explore the clinical evidencehand tremor Find Relief Now
Professionals Explore the Therapy
Real Patient Experiences:4
Cala Trio therapy has made such a difference in my life. I can now hold my book steady as I read. I can cut vegetables with more control, and the best part is being able to eat and drink without it spilling all over me.
Holly Ministry Volunteer & Grandmother
When I look at the results before and after the therapy, the Cala Trio has really improved my tremor. I no longer need to ask my husband for a sip of hot tea.
Yvonne Speech Therapist
I start my Cala Trio therapy first thing in the morning getting the kids off to school. Activities that used to be difficult are easier and more manageable today.
Joyce IT Professional and Mother
After the very first session, I texted my wife with greater ease and then held up my hand thinking to myself, this is what it feels like to be normal.
Bob Tai Chi Aficionado, Retired CFO
Cala Trio in the News


Results of the landmark PROSPECT trial of the Cala Trio, a wrist-worn wearable neuromodulation device for essential tremor (ET), suggest that the device is safe and effective for the reduction of hand tremor in individuals with ET.
- Isaacson SH, et al. Tremor and Other Hyperkinetic Movements. 2020;10:29. doi:10.5334/tohm.59. As measured by Cala device following three months of repeated home use in 205 patients with essential tremor who completed the study. Many participants were also taking medication for their tremor and it was difficult to assess the effect of the device compared to medication.
- Food and Drug Administration (FDA) has cleared the Cala Trio K203288.
- Safety information. The most common reported side effects to include mild to moderate skin irritation, including electrical stimulation burns, redness, and/or itching where the device touched the skin. For comprehensive safety information, visit CalaTrio.com/Safety.
- Patient experiences are summarized from interviews featured on the Cala Health YouTube Channel. Individual results may vary; patients were not compensated for their stories.
MKG-1501 Rev C Oct 2022